Endocrine Abstracts

Although surgical resection is the usual initial treatment for patients with acromegaly, it does not always lead to a remission. Gamma knife radiosurgery (GKRS) is an important additional strategy for unresected clinically active pituitary adenomas.Objective: We evaluated retrospectively pituitary hormone status as well as the efficacy of GKRS for patients with acromegaly referred to our tertiary endocrinology clinic. Prognostic factors related to outcom...

Introduction: Inferior petrosal sinus sampling for ACTH is the current gold standard test for the differentiation of pituitary Cushing disease from the ectopic ACTH syndrome. Early studies with İPSS reported a diagnostic sensitive and specificity approaching 100%, additional experience has shown a false negative rate of 1-10%. This has been due to either technical problem with unsuccessful petrosal sinus catheterization or anomalous venous drainage of the pituitary. The ...

Kidney transplant patients are prone to metabolic bone diseases. In this descriptive clinical study we aimed to evaluate the incidence of osteopenia osteoporosis, vertebral fractures in our group of renal transplant patients.Methods: Eighty seven patients (25 males and 62 females) aged from 20 to 67 years, who had undergone kidney transplantation 1 to 20 yrs. previously included in the study. Bone mineral densitometry was performed using dual-energy X-ra...

AımThe aim of this study is to investigate the attitude of physicians, who are specialized in internal medicine, endocrinology, nurology and cardiology, on LDL target levels and antilipidemic treatments in Turkey.MethodsThis study outlines attitudes of physicians towards the guideline-recommended LDL target levels in diabetic dyslipidemia. An invitaiton to fill a questionnaire on demographic and professi...

İntroductionThe aim of this study was to evaluate the association between fibroblast growth factor-21 (FGF-21) levels and carotid intima media thickness (CIMT) in acromegalic patients in relation to the atherosclerotic complications.Metarials and methodsThe study goroup included 70 acromegalic patients. According to the disease activity, patients cathegorized inti 2 groups: controlled and active acromega...

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...

Introduction: Pachydermoperiostosis (PDP) is a rare hereditary syndrome with familial and idiopathic forms that is characterized by subperiosteal new bone formation with pain, polyarthritis, cutis vertices grata, seborrhea, hyperhidrosis and digital clubbing. Periostosis and cutaneous thickening along with the absence of any signs of cardiovascular, pulmonary, hepatic, intestinal and mediastinal diseases causing secondary hypertrophic osteoarthropathy suggest PDP. The incidenc...

Prevalence of Paget’s disease (PD) of bone as well as clinical and demographical presentation may differ between the populations.Aim: In this study we evaluate clinical and demographical parameters of Paget’s disease patients followed from endocrinology clinics in Turkey.Method: An invitation was sent to all tertiary endocrinology clinics to complete a survey on demographic clinical, laboratory parameters, treatment modal...

Aim: The most common clinical presentation of primary hyperparathyroidism (PHPT) is asymptomatıc and it is diagnosed incidentally without developing complications.In our study, we aimed to examine the characteristics of participants with primary hyperparathyroidism and the relationship between bone mineral density (BMD) and hypercalciuria.Methods: Consecutive 191 normocalciuric (24-h urinary calcium<400 mg/day) patients with PHPT (51±13 yea...

Aim: Clinical presentation of primary hyperparathyroidism (PHPT) differs between populations. In this study, we aimed to examine bone mineral density (BMD) and bone metabolism parameters in newly diagnosed and untreated PHPT patients in a single endocrine center in İstanbul, Turkey.Methods: Consecutive 256 PHPT patients (50.7±14 years, F/M:205/51) and 89 healthy controls (38.8±10 years, F/M:67/22) were included in the study. Serum calcium...